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🛡️ Stay ahead of pests with the #1 trusted shield for your giant best friend!
FRONTLINE Plus Flea & Tick Spot Treatment for X-Large Dogs delivers fast, waterproof, and month-long protection against fleas, ticks, chewing lice, and sarcoptic mange. Trusted by pet owners for over two decades, its dual active ingredients (fipronil and (S)-methoprene) break the flea life cycle with a single monthly topical application that covers your dog’s entire body, even through water exposure.

















| ASIN | B07NGXYVZZ |
| ASIN | B07NGXYVZZ |
| Active Ingredients | fipronil and (S)-methoprene |
| Age Range Description | All Life Stages |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #1,922 in Pet Supplies ( See Top 100 in Pet Supplies ) #14 in Dog Flea Drops |
| Brand Name | Frontline |
| Customer Reviews | 4.4 4.4 out of 5 stars (15,498) |
| Date First Available | February 7, 2019 |
| Dog Breed Size | Giant |
| Included Components | Applicator |
| Item Form | Liquid |
| Item Type Name | Topical Red box |
| Item Weight | 1.12 ounces |
| Item model number | 72220 |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer | Boehringer Ingelheim Animal Health |
| Manufacturer Part Number | 72220 |
| Model Number | 72220 |
| Product Dimensions | 1 x 5.75 x 4.5 inches; 1.12 ounces |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 611030624793 350604062479 |
| Unit Count | 1 Count |
| Volume | 32 ml |
| Warranty Description | If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at: 1-800-660-1842. |
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