---
product_id: 168095151
title: "Pro-Resolving Mediators SPM Softgels, 30 Count | Supports the Body's Natural Post-Inflammatory Response with 18-HEPE, 17-HDHA & 14-HDHA; Gluten Free & Non-GMO Softgels"
brand: "life extension"
price: "₨16701"
currency: LKR
in_stock: true
reviews_count: 10
category: "Life Extension"
url: https://www.desertcart.lk/products/168095151-pro-resolving-mediators-spm-softgels-30-count-supports-the-bodys
store_origin: LK
region: Sri Lanka
---

# Gluten-free & Non-GMO purity 3 key PRMs blend Supports natural inflammation balance Pro-Resolving Mediators SPM Softgels, 30 Count | Supports the Body's Natural Post-Inflammatory Response with 18-HEPE, 17-HDHA & 14-HDHA; Gluten Free & Non-GMO Softgels

**Brand:** life extension
**Price:** ₨16701
**Availability:** ✅ In Stock

## Summary

> 🧪 Unlock your body’s natural reset with every softgel!

## Quick Answers

- **What is this?** Pro-Resolving Mediators SPM Softgels, 30 Count | Supports the Body's Natural Post-Inflammatory Response with 18-HEPE, 17-HDHA & 14-HDHA; Gluten Free & Non-GMO Softgels by life extension
- **How much does it cost?** ₨16701 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.lk](https://www.desertcart.lk/products/168095151-pro-resolving-mediators-spm-softgels-30-count-supports-the-bodys)

## Best For

- life extension enthusiasts

## Why This Product

- Trusted life extension brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Immune Harmony Booster:** Maintains optimal cytokine balance to support your body’s natural defense system
- • **Cellular Renewal Catalyst:** Boosts natural pathways to clear cellular debris and rejuvenate vital tissues
- • **Clean & Conscious Formula:** Gluten-free, Non-GMO, and crafted with premium raw ingredients in the USA
- • **Clinically Inspired Dosage:** Formulated based on cutting-edge scientific research for maximum efficacy
- • **Precision Pro-Resolving Blend:** Harnesses 18-HEPE, 17-HDHA & 14-HDHA for targeted post-inflammatory support

## Overview

Life Extension Pro-Resolving Mediators delivers a scientifically formulated blend of specialized pro-resolving mediators (18-HEPE, 17-HDHA, 14-HDHA) designed to support your body’s natural post-inflammatory response. This gluten-free, non-GMO supplement promotes healthy tissue rejuvenation, cellular debris clearance, and immune balance, empowering you to maintain joint, heart, and overall inflammation health with a clean, premium formula trusted by thousands.

## Description

The body creates specialized pro-resolving mediators (PRMs) from fatty acids such as EPA and DHA omega-3s. It then uses those pro-resolving mediators to promote a healthy post-inflammatory response, supporting healthy tissue rejuvenation and maintaining the vital balance between cytokine compounds. This formula combines PRMs and PRM precursors.

Review: works for pain - goood supplement and has cut my pain down and thats a plus
Review: Great purchase - Easy to take and helpful.

## Features

- Tissue rejuvenation - The body uses compounds called specialized pro-resolving mediators (called PRMs) to support the natural process for revitalizing skin, organs, and other vital tissues.
- Cellular debris - The body uses PRMs to encourage existing pathways for naturally removing cellular debris, as well as recycling cells that no longer function optimally.
- Maintain balance - The body uses PRMs to maintain a natural, healthy balance between cytokines compounds, which are released by immune cells to govern a variety of processes.
- Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Live your healthiest life - We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B07YN6NK66 |
| Age Range Description | Adult |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #19,039 in Health & Household ( See Top 100 in Health & Household ) #492 in Blended Vitamin & Mineral Supplements |
| Brand | Life Extension |
| Brand Name | Life Extension |
| Color | Light Golden |
| Container Type | Bottle |
| Customer Reviews | 4.5 out of 5 stars 495 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Softgel |
| Flavor | Unflavored |
| Item Dimensions | 1.86 x 1.86 x 3.41 inches |
| Item Form | Softgel |
| Item Nype Name | Pro-Resolving Mediators |
| Item Weight | 1 ounces |
| Manufacturer | AmazonUs/LJHZZ |
| Manufacturer Part Number | 02223 |
| Material Features | GMO Free |
| Material Type Free | Gluten Free |
| Model Name | Pro-Resolving Mediators |
| Model Number | 02223 |
| Number of Items | 1 |
| Primary Supplement Type | Pro-Resolving Mediators |
| Product Benefits | Encourage the body’s natural processes for healthy tissue rejuvenation, Help maintain the body’s natural balance between cytokine compounds, Promote the body’s natural pathways for clearing cellular debris |
| Recommended Uses For Product | Healthy Joints, Heart Health, Inflammation Management, Joint Health |
| Special Ingredients | Marine Lipid Concentrate |
| Specific Uses For Product | Healthy Joints, Heart Health, Inflammation Health Support, Joint Health |
| Total Servings Per Container | 30 |
| UPC | 737870222330 |
| Unit Count | 30 Count |

## Product Details

- **Brand:** Life Extension
- **Diet Type:** Gluten Free
- **Flavor:** Unflavored
- **Item Form:** Softgel
- **Item Weight:** 1 ounces
- **Item dimensions L x W x H:** 1.86 x 1.86 x 3.41 inches
- **Primary Supplement Type:** Pro-Resolving Mediators
- **Special Ingredients:** Marine Lipid Concentrate
- **Unit Count:** 30 Count

## Images

![Pro-Resolving Mediators SPM Softgels, 30 Count | Supports the Body's Natural Post-Inflammatory Response with 18-HEPE, 17-HDHA & 14-HDHA; Gluten Free & Non-GMO Softgels - Image 1](https://m.media-amazon.com/images/I/71O8T+BwXoL.jpg)

## Available Options

This product comes in different **Style** options.

## Questions & Answers

**Q: What are pro resolving mediators?**
A: Resolvins and maresins are the two principal kinds of specialized pro-resolving mediators (PRMs, also known as SPMs). The body uses them for everything from tissue rejuvenation to cellular cleanup.

**Q: Are pro resolving mediators ok to take with other supplements?**
A: Pro resolving mediator supplements are generally OK to take with other supplements. We suggest taking pro resolving mediators with a high quality curcumin from turmeric supplement.

**Q: Can I get pro resolving mediators from fish oil?**
A: Yes, you can get pro-resolving mediators from fish oil. So why not just take a fish oil supplement? Because unlike these novel compounds, fish oil may not support PRM levels sufficiently.

## Customer Reviews

### ⭐⭐⭐⭐⭐ works for pain
*by J***I on September 12, 2025*

goood supplement and has cut my pain down and thats a plus

### ⭐⭐⭐⭐⭐ Great purchase
*by K***D on December 23, 2025*

Easy to take and helpful.

### ⭐⭐⭐⭐⭐ Cleans your body of cellular waste.
*by S***T on March 25, 2026*

I don not take this to mediate pain, nor have I noticed any pain relief from this product. This supplimenint remove damaged tissue, etc. from your body, and does not reduce inflamation. It doesn't mask pain, it finds the source and removes waste and deritria from the body.

## Frequently Bought Together

- Life Extension Pro-Resolving Mediators - Inflammation Management and Joint Health Supplement -Whole Body Health Support - From Marin Oil PRMs SPMs - Gluten-Free, Non-GMO, 30 Softgels
- Life Extension Cytokine Suppress with EGCG - Inflammation Management Supplement - For Immune System Response - Non-GMO, Gluten-Free - 30 Vegetarian Capsules
- Life Extension N-Acetyl-L-Cysteine (NAC), Immune Response, Respiratory Health, Liver Health, NAC 600 mg, antioxidant Defense, Free radicals, Easy to Absorb, 60 Capsules

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*Product available on Desertcart Sri Lanka*
*Store origin: LK*
*Last updated: 2026-09-10*