---
product_id: 37274590
title: "Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram"
brand: "differin"
price: "₨10166"
currency: LKR
in_stock: false
reviews_count: 2
url: https://www.desertcart.lk/products/37274590-differin-adapalene-prescription-strength-retinoid-gel-0-1-acne-treatment
store_origin: LK
region: Sri Lanka
---

# water-based, oil & alcohol free formula up to 87% acne lesion reduction in 12 weeks 0.1% adapalene penetrates deep pores Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram

**Brand:** differin
**Price:** ₨10166
**Availability:** ❌ Out of Stock

## Summary

> ✨ Clear skin, confident you — join the skincare revolution!

## Quick Answers

- **What is this?** Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram by differin
- **How much does it cost?** ₨10166 with free shipping
- **Is it available?** Currently out of stock
- **Where can I buy it?** [www.desertcart.lk](https://www.desertcart.lk/products/37274590-differin-adapalene-prescription-strength-retinoid-gel-0-1-acne-treatment)

## Best For

- differin enthusiasts

## Why This Product

- Trusted differin brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Deep Pore Power:** Targets acne at its root for lasting clarity
- • **Clean & Lightweight:** Water-based, oil-free, fragrance-free formula fits any routine
- • **Gentle Yet Effective:** Adapalene retinoid designed for superior skin tolerance
- • **Clinically Proven Results:** Up to 87% fewer acne lesions in just 12 weeks
- • **Prevents Scarring & Hyperpigmentation:** Protects your skin’s future while clearing current breakouts

## Overview

Differin Adapalene 0.1% Gel is the first prescription-strength retinoid acne treatment available OTC in 30+ years. It normalizes skin cell turnover to clear and prevent acne by targeting clogged pores and inflammation. Clinically proven to reduce acne lesions by up to 87% in 12 weeks, its water-based, oil- and fragrance-free formula offers superior tolerability and helps prevent scarring and hyperpigmentation, making it ideal for professional millennials seeking effective, dermatologist-recommended skincare.

## Description

Differin Gel is the First New acne active ingredient available over the counter in over 30 years and is the First and strength retinoid acne treatment Now Available without a prescription. Differin Gel contains adapalene, a multi-benefit dermatologist recommended retinoid that clears and prevents acne, which helps restore skin’s natural tone and texture.

Review: I am leaving a long review to hopefully help someone - we all deserve clear skin! - tl;dr: 10/10 recommend, leaves my skin smooth, no breakouts since I started. Def wash your hands after applying, as small traces will transfer on other parts of your skin if you touch - I got a reaction this way on my arm and knee. Once I started washing my hands after use, no problem. I also find myself using a bigger scoop of face lotion as it does dry me out a bit. A quick backstory about my skincare. I had horrible acne as a kid. After high school, thinking it would always just get better, my mom took me to a dermatologist to get treatment. For reference, my acne was so bad the first recommendation was Accutane. Thankfully, my mom said no, and I went on antibiotics that helped clear me up. Additionally, I’m a night shower girly, so I apply this at night with all my skincare, not in the morning. I’d say I’m normal skin but slightly oily in the t-zone. Now, 27, I’m trying to just get nicer looking skin. I’ll get a break out during my period of 1-3 pimples, all hormonal and really what can you do lol, but sometimes I just get that nasty cyst and want to cry. Years of horrible cystic acne has just left me with poor skin texture as I was a picker, so I’m looking to improve it. I also just have large pores on my nose and a bit on my chin. 7/23 - Got the Differin gel. This is my timeline of use. 7/28, about a week in, and I felt the side effects of the tingling/burning. This only was prominent when I put my skincare on, lasted less than 20 seconds. In the morning when I put on spray sunscreen it also burned. The burning feeling is very minimal, 5-10 seconds. I overall have sensitive skin everywhere, not just my face. This was a prime side effect when I read up on use. One thing I did notice is I was a bit more dry than usual, developing dry patches (pretty small, flaked right off and not itchy) and the unevenness in my skin seemed to be more prominent - I looked more red and splotchy. My skin just got really irritated more since using. Online reviews recommend 2-4 weeks of these symptoms and needing to get through the month, so that’s the goal! 8/1, almost two weeks, redness flair has died down and burning is noticeable less when makeup or skincare/lotion is applied. Dry skin and the patchyness is about the same. 8/8 - Burning feeling is gone. One thing is that I apply this at night after I shower (night showers) and then I apply my body lotion. That small residue that is going on my body has caused parts to get really dry and small pimples. Make sure if you are applying this that you are washing your hands afterwards before you apply anything else on another part of your body. The dryness on my arms killed! 8/25 - Overall, my skin always feels smooth! I would wake up in the morning and where I have larger pores it would feel bumpy, but not anymore! Will continue to use!
Review: Works for rosacea, but took a while! - Ok, to begin, give this stuff about 2-3 weeks of use before judging it. Secondly, I use this for rosacea, not acne, so if you are looking to use it for that, keep reading. I was diagnosed with rosacea about a year and a half ago. I get rough red bumps on my cheeks and forehead. They aren't super noticeable, but they make my skin not look as smooth and sometimes get worse depending on what I eat/drink. My dermatologist wrote me a prescription for Finacea foam, but the cost of it keeps going up. I was paying $240 a month for it. Rosacea is considered a cosmetic condition, not something detrimental to your health, so insurance doesn't help out a lot for the meds. Anyway, after getting sick of paying so much for a prescription, I started looking at other options. On a rosacea forum I saw a dermatologist recommend Differin and decided to try it. Here's my experience. The first two weeks were hell. I put on Differin every night before bed and it would burn the heck out of my face. My cheeks would get redder, my skin would feel overly tight and almost like I had a sunburn, and the dryness was unstoppable. No matter how much lotion I put on my skin was constantly flaking.Then on top of that, from the constant lotion use I started to get pimples. I never get pimples. Ugh!! I honestly only "hung in there" out of desperation. After about roughly 2 weeks of use, my face stopped drying out, and the rosacea is just as minimized as when I was using the prescription foam. I am so thankful I stuck with this! I do not have to constantly slather on lotion, and my skin looks great. If I may suggest a tip though...use a good facial cleanser in the shower that smooths your skin. I started using Cetaphil in the shower on my face and it has done wonders in combination with the Differin. The Cetaphil was cheap (roughly $6 at Target) and it makes my skin soft and clean while the differin keeps the rosacea away. I've attached a picture from this morning, after about 3 weeks of Differin use. It is a super close up so you can see how smooth my skin looks. Yes, I have a lot of pinkness in my cheeks still due to the rosacea, but I don't mind that...I only mind the gross bumps I get that make me look like Freddy Krueger. I hope this review is helpful if you are suffering like I was. Best of luck to you on your journey to fight rosacea.

## Features

- Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
- Differin works differently than other Acne treatments by normalizing skin cell turnover and effectively targets two primary causes of Acne, clogged pores and inflammation
- Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
- Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating Acne
- In a clinical study, Differin gel provided up to 87 percent reduction in acne lesions after 12 weeks, which will continue to improve with further use

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN  | B01M114813 |
| Best Sellers Rank | #90,644 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #211 in Facial Cleansing Gels #3,547 in Facial Treatments & Masks |
| Customer Reviews | 4.6 4.6 out of 5 stars (4,025) |
| Is Discontinued By Manufacturer  | No |
| Manufacturer  | Galderma Laboratories, Inc |
| Product Dimensions  | 3.19 x 3.94 x 7.44 inches; 1.6 ounces |
| UPC  | 302994910458 |

## Images

![Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram - Image 1](https://m.media-amazon.com/images/I/41+1E+PAAML.jpg)
![Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram - Image 2](https://m.media-amazon.com/images/I/41UcWtTvd8L.jpg)
![Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram - Image 3](https://m.media-amazon.com/images/I/518eKkN9saL.jpg)
![Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram - Image 4](https://m.media-amazon.com/images/I/518ws0JXQML.jpg)
![Differin Adapalene Prescription Strength Retinoid Gel 0.1% Acne Treatment (Up to 90 Day Supply), 45 Gram - Image 5](https://m.media-amazon.com/images/I/51mIVRMBoIL.jpg)

## Questions & Answers

**Q: Is this good for aging skin with NO acne problem?**
A: It's main indication is for acne. However, there are scholarly articles in dermatology journals, which I have open access to as a student, related to the effect of adapalene on aging skin with good results. There is also a dermatologist on YouTube using this as her first retinoid on herself and explains the difference between this and a retinol, while this could be considered not quite as credible because of it being on YouTube. There is information if you seek it out, though not as much as tretinoin on this particular topic. I have no aversion to spending money on my skin if the product works, and I would still try this over a $100 retinol product at Sephora.

**Q: Can this be used for aging skin?**
A: According to a dermatologist-Differin is a fantastic anti-aging product as it stimulates collagen production by cells in our dermis (the deeper layer of the skin),”  "This is what helps with fine lines and overall skin thickness." ... It's also the same ingredient that helps improve skin discoloration, texture and tone. It can take anywhere from 3-12 months to see improvement, but I can tell you it helped me immensely. Lightened my dark brown spots and smoothed my fine lines. It took about 3 months of every day usage to see results

**Q: Is this the same differin that I was prescribed by my dermatologist years ago?**
A: Hi Jenn, thanks for asking! Yes- Differin® Gel is the same powerful, acne-fighting formula, now even more accessible and at an affordable price. It is the first FDA approved, over the counter product to contain adapalene, the prescription strength retinoid in Differin Gel.  We hope you decide to try the product, and please feel free to reach out to our team if you have additional questions: gss@galdermaservices.com or 1-866-735- 4137 (M-F, 8a-5p CT).

**Q: How much do you use every night? Dime size, quarter size, line across your finger?**
A: Hi there! For best results, we recommend washing your face with a gentle, non-drying cleanser, such as Differin® Balancing Cleanser, applying a thin layer of Differin Gel to clean, dry skin (full face). No more than a pea-sized amount of gel should be applied in a thin layer to the face once daily. Follow the treatment with a moisturizer and SPF. We hope this is helpful!

## Customer Reviews

### ⭐⭐⭐⭐⭐ I am leaving a long review to hopefully help someone - we all deserve clear skin!
*by L***N on August 25, 2024*

tl;dr: 10/10 recommend, leaves my skin smooth, no breakouts since I started. Def wash your hands after applying, as small traces will transfer on other parts of your skin if you touch - I got a reaction this way on my arm and knee. Once I started washing my hands after use, no problem. I also find myself using a bigger scoop of face lotion as it does dry me out a bit. A quick backstory about my skincare. I had horrible acne as a kid. After high school, thinking it would always just get better, my mom took me to a dermatologist to get treatment. For reference, my acne was so bad the first recommendation was Accutane. Thankfully, my mom said no, and I went on antibiotics that helped clear me up. Additionally, I’m a night shower girly, so I apply this at night with all my skincare, not in the morning. I’d say I’m normal skin but slightly oily in the t-zone. Now, 27, I’m trying to just get nicer looking skin. I’ll get a break out during my period of 1-3 pimples, all hormonal and really what can you do lol, but sometimes I just get that nasty cyst and want to cry. Years of horrible cystic acne has just left me with poor skin texture as I was a picker, so I’m looking to improve it. I also just have large pores on my nose and a bit on my chin. 7/23 - Got the Differin gel. This is my timeline of use. 7/28, about a week in, and I felt the side effects of the tingling/burning. This only was prominent when I put my skincare on, lasted less than 20 seconds. In the morning when I put on spray sunscreen it also burned. The burning feeling is very minimal, 5-10 seconds. I overall have sensitive skin everywhere, not just my face. This was a prime side effect when I read up on use. One thing I did notice is I was a bit more dry than usual, developing dry patches (pretty small, flaked right off and not itchy) and the unevenness in my skin seemed to be more prominent - I looked more red and splotchy. My skin just got really irritated more since using. Online reviews recommend 2-4 weeks of these symptoms and needing to get through the month, so that’s the goal! 8/1, almost two weeks, redness flair has died down and burning is noticeable less when makeup or skincare/lotion is applied. Dry skin and the patchyness is about the same. 8/8 - Burning feeling is gone. One thing is that I apply this at night after I shower (night showers) and then I apply my body lotion. That small residue that is going on my body has caused parts to get really dry and small pimples. Make sure if you are applying this that you are washing your hands afterwards before you apply anything else on another part of your body. The dryness on my arms killed! 8/25 - Overall, my skin always feels smooth! I would wake up in the morning and where I have larger pores it would feel bumpy, but not anymore! Will continue to use!

### ⭐⭐⭐⭐⭐ Works for rosacea, but took a while!
*by G***1 on April 28, 2017*

Ok, to begin, give this stuff about 2-3 weeks of use before judging it. Secondly, I use this for rosacea, not acne, so if you are looking to use it for that, keep reading. I was diagnosed with rosacea about a year and a half ago. I get rough red bumps on my cheeks and forehead. They aren't super noticeable, but they make my skin not look as smooth and sometimes get worse depending on what I eat/drink. My dermatologist wrote me a prescription for Finacea foam, but the cost of it keeps going up. I was paying $240 a month for it. Rosacea is considered a cosmetic condition, not something detrimental to your health, so insurance doesn't help out a lot for the meds. Anyway, after getting sick of paying so much for a prescription, I started looking at other options. On a rosacea forum I saw a dermatologist recommend Differin and decided to try it. Here's my experience. The first two weeks were hell. I put on Differin every night before bed and it would burn the heck out of my face. My cheeks would get redder, my skin would feel overly tight and almost like I had a sunburn, and the dryness was unstoppable. No matter how much lotion I put on my skin was constantly flaking.Then on top of that, from the constant lotion use I started to get pimples. I never get pimples. Ugh!! I honestly only "hung in there" out of desperation. After about roughly 2 weeks of use, my face stopped drying out, and the rosacea is just as minimized as when I was using the prescription foam. I am so thankful I stuck with this! I do not have to constantly slather on lotion, and my skin looks great. If I may suggest a tip though...use a good facial cleanser in the shower that smooths your skin. I started using Cetaphil in the shower on my face and it has done wonders in combination with the Differin. The Cetaphil was cheap (roughly $6 at Target) and it makes my skin soft and clean while the differin keeps the rosacea away. I've attached a picture from this morning, after about 3 weeks of Differin use. It is a super close up so you can see how smooth my skin looks. Yes, I have a lot of pinkness in my cheeks still due to the rosacea, but I don't mind that...I only mind the gross bumps I get that make me look like Freddy Krueger. I hope this review is helpful if you are suffering like I was. Best of luck to you on your journey to fight rosacea.

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*Product available on Desertcart Sri Lanka*
*Store origin: LK*
*Last updated: 2026-02-09*