---
product_id: 543984741
title: "ISDIN Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml)"
brand: "isdin"
price: "₨135576"
currency: LKR
in_stock: true
reviews_count: 8
category: "Isdin"
url: https://www.desertcart.lk/products/543984741-isdin-isdinceutics-retinal-advanced-rejuvenating-facial-night-serum-with-retinaldehyde
store_origin: LK
region: Sri Lanka
---

# 43% wrinkle reduction in 4 weeks Night serum with melatonin for skin rejuvenation Dual-phase formula for maximum ingredient stability ISDIN Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml)

**Brand:** isdin
**Price:** ₨135576
**Availability:** ✅ In Stock

## Summary

> 🌟 Wake up to younger, glowing skin — because your nights deserve a glow-up!

## Quick Answers

- **What is this?** ISDIN Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml) by isdin
- **How much does it cost?** ₨135576 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.lk](https://www.desertcart.lk/products/543984741-isdin-isdinceutics-retinal-advanced-rejuvenating-facial-night-serum-with-retinaldehyde)

## Best For

- isdin enthusiasts

## Why This Product

- Trusted isdin brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Nighttime Skin Renewal:** Melatonin-infused serum works overnight to smooth texture and restore radiance while you sleep.
- • **Gentle Yet Powerful Retinoid:** Retinaldehyde delivers potent anti-aging benefits without the harsh irritation typical of retinol, perfect for all skin types.
- • **Clinically Proven Youth Boost:** Clinically shown to reduce wrinkles by 43% in just 4 weeks, turning back the clock on fine lines and loss of firmness.
- • **Advanced Dual-Phase Technology:** Innovative two-phase formula keeps retinaldehyde and melatonin ultra-stable and highly effective for sensitive skin.
- • **Visible Glow & Hydration Boost:** Experience softer, more hydrated skin with improved tone and subtle luminosity that sets you apart.

## Overview

ISDIN Isdinceutics Retinal Advanced is a 50ml rejuvenating night serum formulated with retinaldehyde and melatonin. Clinically proven to reduce wrinkles by 43% in 4 weeks, its dual-phase technology ensures ingredient stability and effectiveness for all skin types, including sensitive skin. This serum smooths skin texture, boosts hydration, and enhances radiance, making it a premium anti-aging solution for professionals seeking visible, youthful skin transformation.

## Description

desertcart.com: ISDIN Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml) : Beauty & Personal Care

Review: First Retinoid Product - so far so good! - I’ve never used retinal/retinol etc, so using this product is my very first attempt. I am 40+, fair skin, sensitive skin, dry skin, med/large pores, still prone to hormonal breakouts, some sun damage freckling, pretty deep 11s, and very minor wrinkles anywhere else. I started using this right around 2/1/24. It’s now 2 months of almost nightly use since (I’ve skipped a couple nights here or there just from schedule issues). I do use a full 2 pumps each time, every night, and I run the excess down my neck and upper chest to help with signs of aging there. I thought FOR SURE I would have bad peeling, redness, etc because I have sensitive skin and usually EVERYTHING makes me red or break out. But this hansy been bad at all! I started to think that might mean it’s a dud product, but I have been going thru “purge” for about 3-4 weeks. Not constant, but a couple of rounds of very agitated pimples. Moreso than I usually get, and I am used to have them every month with my cycle. So that makes me feel like it’s doing SOMETHING! I think I may be on the downward slope of the purge…. Hopefully. How does my skin feel or look? Well, it actually does feel more hydrated and softer than ever. I love that! It looks slightly more even tone (between the breakout areas when I’m having pimples and generally all over when I’m not having a breakout.) I also feel like I’m seeing a little more radiance or glow. Nothing miraculous, but just a little more shine and luster. I have not noticed a reduction in my deep 11s or my 2 very fine forehead lines. So far I’m happy. It’s such an expensive product I hate that you have to spend so much to find out if it works, but I feel like the signs I’m seeing now support continued use and expense. At 2 months, it looks to me like I might have 1 month of product left in the jar. For the price I paid, if it lasts 3 months, that’s about $62 a month ($744 a year!). I’ve never had an rx from a derm, so I’m not sure how that compares to prescription and office visit costs. I’m going to continue trying this for the full year. If I feel confident that I’m seeing results, I’ll do a cost comparison of actually getting on and maintaining a retinoid rx or just continuing this product. Will update!
Review: I love it - Value for money, effectiveness, excellent texture.

## Features

- YOUR SOLUTION FOR: Fine lines and wrinkles, loss of elasticity and firmness, dullness
- KEY INGREDIENT: A very effective retinoid, retinaldehyde demonstrates powerful youth-boosting properties
- ACTION: Smoothes skin texture for visibly younger-looking skin
- TESTED: Advanced formula tested for all skin types, including sensitive skin
- TECHNOLOGY: Separates ingredients into two phases to keep formula stable and effective
- RESULTS: Clinical results show -43% of wrinkles after 4 weeks

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0CC9W3VWR |
| ASIN  | B0CC9W3VWR |
| Age Range Description | Adult |
| Best Sellers Rank | #50,675 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #1,041 in Facial Serums |
| Brand Name | ISDIN |
| Customer Reviews | 4.5 4.5 out of 5 stars (194) |
| Department  | womens |
| Item Form | Cream |
| Item Volume | 1.7 Fluid Ounces |
| Manufacturer | ISDIN |
| Manufacturer  | ISDIN |
| Number of Items | 1 |
| Package Dimensions  | 7.09 x 4.13 x 3.35 inches; 9.59 ounces |
| Product Benefits | Retinal Advanced is a night serum that helps visibly reduce wrinkles and fine lines. Formulated with youth-boosting ingredients such as retinaldehyde, it helps smooth and rejuvenate the skin. |
| Recommended Uses For Product | Wrinkles |
| Skin Type | All |
| Special Ingredients | vitamin_e |
| Specific Uses For Product | Apply at night onto clean, dry skin. Press pump twice to dispense the right amount into hand, mix well, and apply. Always apply a broad spectrum sunscreen the next morning and throughout the day. |
| Target Use Body Part | Skin |
| Unit Count | 1.7 Fluid Ounces |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** ISDIN
- **Item Volume:** 1.7 Fluid Ounces
- **Number of Items:** 1
- **Skin Type:** All

## Images

![ISDIN Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml) - Image 1](https://m.media-amazon.com/images/I/51pcEQVydwL.jpg)

## Questions & Answers

**Q: Is Retinal Advanced suitable for sensitive skin?**
A: Yes! It’s suitable for all skin types. Retinal Advanced has been clinically tested on a wide range of skin types, including sensitive skin

**Q: Can I use it day and night?**
A: The use of retinoids can make the skin more sensitive to external factors, meaning that the effect of sun exposure can be more intense. For this reason, we recommend using it at night, followed by a broad spectrum sunscreen in the morning.

**Q: Can I use it at any time of the year?**
A: Yes, once your skin is retinized, you can use Retinal Advanced at night all year round. No matter the time of year: always apply sun protection the next morning!

## Customer Reviews

### ⭐⭐⭐⭐⭐ First Retinoid Product - so far so good!
*by R***B on April 6, 2024*

I’ve never used retinal/retinol etc, so using this product is my very first attempt. I am 40+, fair skin, sensitive skin, dry skin, med/large pores, still prone to hormonal breakouts, some sun damage freckling, pretty deep 11s, and very minor wrinkles anywhere else. I started using this right around 2/1/24. It’s now 2 months of almost nightly use since (I’ve skipped a couple nights here or there just from schedule issues). I do use a full 2 pumps each time, every night, and I run the excess down my neck and upper chest to help with signs of aging there. I thought FOR SURE I would have bad peeling, redness, etc because I have sensitive skin and usually EVERYTHING makes me red or break out. But this hansy been bad at all! I started to think that might mean it’s a dud product, but I have been going thru “purge” for about 3-4 weeks. Not constant, but a couple of rounds of very agitated pimples. Moreso than I usually get, and I am used to have them every month with my cycle. So that makes me feel like it’s doing SOMETHING! I think I may be on the downward slope of the purge…. Hopefully. How does my skin feel or look? Well, it actually does feel more hydrated and softer than ever. I love that! It looks slightly more even tone (between the breakout areas when I’m having pimples and generally all over when I’m not having a breakout.) I also feel like I’m seeing a little more radiance or glow. Nothing miraculous, but just a little more shine and luster. I have not noticed a reduction in my deep 11s or my 2 very fine forehead lines. So far I’m happy. It’s such an expensive product I hate that you have to spend so much to find out if it works, but I feel like the signs I’m seeing now support continued use and expense. At 2 months, it looks to me like I might have 1 month of product left in the jar. For the price I paid, if it lasts 3 months, that’s about $62 a month ($744 a year!). I’ve never had an rx from a derm, so I’m not sure how that compares to prescription and office visit costs. I’m going to continue trying this for the full year. If I feel confident that I’m seeing results, I’ll do a cost comparison of actually getting on and maintaining a retinoid rx or just continuing this product. Will update!

### ⭐⭐⭐⭐⭐ I love it
*by M***E on January 29, 2026*

Value for money, effectiveness, excellent texture.

### ⭐⭐⭐⭐⭐ Good product
*by H***A on February 12, 2026*

Make my skin soft

## Frequently Bought Together

- ISDIN Isdinceutics Retinal Advanced - Rejuvenating Facial Night Serum with Retinaldehyde and Melatonin 1.7 FL OZ (50 ml)
- ISDIN Eryfotona Actinica Zinc Oxide and 100% Mineral Sunscreen Broad Spectrum SPF 50+, No White Cast, Suitable for Sensitive Skin
- Vitamin C and Hyaluronic Acid Serum ampoule, Flavo-C Ultraglican by ISDIN

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*Product available on Desertcart Sri Lanka*
*Store origin: LK*
*Last updated: 2026-03-10*